NAME:
ORISH EBERE ORISAKWE
NATIONALITY: Nigerian
B.Sc. (Hons) Biochemistry, University of Nigeria, Nsukka (1984)
M.Sc. Pharmacology/Toxicology, University of
Lagos, Nigeria (1987)
M.Phil. Pharmacology/Toxicology, University of
Lagos, Nigeria (1990)
Ph.D. Pharmacology/Toxicology, University of
Nigeria, Nsukka (l997)
Nnamdi
Azikiwe University
Nnewi Campus
P.M.B.5001, Nnewi,
Anambra State, Nigeria
Tel: +234(0)8035510063
Fax: +234-046-460124
RECORDS: EMPLOYMENT
::
1987-1988 Research Assistant:
College of Medicine, University of Lagos
Idiaraba, Nigeria.
Job
Description:
I was involved in rotational posting in all the ongoing researches in the
Department of Pharmacology and Toxicology. I worked in the following Laboratories
in the department:
• Ethnopharmacology
• Endocrine / Metabolism
• Chemotherapy
• Pharmacokinetics
• Toxicology
I was also involved in the teaching of Pharmacology to Pharmacology, Physiology, Dentistry, Pharmacy and Medical Students.
::
1988 - 1990 Graduate
Research Assistant
Toxicology Research Laboratories, College of Medicine, University of Lagos,
Idiaraba, Nigeria.
Job Description: I was permanently attached to the Toxicology Research Laboratories where I was involved in consultancy services, organization of seminars and workshops on Environmental Toxicology. I was also involved in supervision of undergraduate.
::
1990-1993 Lecturer:
Department of Pharmacology,
Nnamdi Azikiwe University, Nnewi Campus.
Job Description:
I was involved in teaching and research.
::
1994-present Senior Lecturer
Department of Pharmacology, Nnamdi Azikiwe University, Nnewi Campus.
Job
Description: I have
been teaching undergraduate and postgraduate students. I have also been involved
in active supervision of postgraduate students and interdepartmental supervision
of postgraduate students. My current research interests include:
•
Reproductive Toxicology:
Testicular toxicity of metals and heavy
metal in Nigerian traditional herbal remedies.
•
Reproductive toxicology
of petroleum products .
•
Ecotoxicology of some
rivers in Nigeria.
•
Water and soil
qualities of highly industrialised cities in
Nigeria. etc.
As
Head, Department of
Pharmacology 1994 - 2000, 1 was involved in day-to-day administration of the
department. Other positions of responsibility bordering on trust and honesty
were entrusted to me. My list of publications (more than 90 articles) spread
out in notable journals around the globe.
PERSONAL DETAILS
SURNAME:
Orisakwe
OTHER NAMES: Livinus Orish Ebere
GENDER: Male
NATIONALITY: Nigerian
PLACE OF BIRTH: Lagos, Nigeria
DATE OF BIRTH: March 1, 1962
MARITAL STATUS: Married
NUMBER OF CHILDREN: 4
NEXT OF KIN:
Dr (Mrs.) Chinna N. Orish
Nnamdi Azikiwe University Teaching Hospital
Nnewi, Anambra State, Nigeria.
SCHOOLS ATTENDED WITH DATES
(1) University of Nigeria, Nsukka (1980 - 1984)
(2) University of Lagos, Nigeria (1986 - 1990)
(3) University of Nigeria, Nsukka (1992 - 1997)
ACADEMIC
QUALIFICATIONS
(1) B.Sc (Hons) Biochemistry
(2) M.Sc Pharmacology/Toxicology
(3) M.Phil. Pharmacology /Toxicology
(4) Ph.D. Pharmacology/Toxicology
BIOGRAPHICAL REFERENCE LISTINGS/AWARDS
* Marquis Who’s Who in the World.
* IBC Nominated, Outstanding People of the 20th
Century (CAMBRIDGE)
* Marquis Who’s Who in Medicine and Healthcare
* American Biographical Institute, Research Board
of Advisors.
* American Biographical Institute, MAN OF THE
YEAR 2000.
* American Biographical Institute, International
Directory of
Distinguished Leadership,
HALL OF FAME
* Marquis Who’s Who in Science and Engineering
2000.
* American Biographical Institute Medal Award.
* International Peace Prize, United
Cultural Convention of the
United States of America
* American Biographical Institute, MAN OF THE
YEAR 2005.
MEMBERSHIP
OF INTERNATIONAL BODIES
(1) American Association for Advancement of
Science (AAAS)
(2) Society of Toxicology, (SOT), Washington,
USA
(3) New York Academy of Science (NYAS)
(4) African Society for Toxicological
Sciences (ASTS), Nigerian
Coordinator 2000-2002
(5) AFRICACLEAN (World Bank Assisted
Group for the use of Leaded
Gasoline in sub Saharan Africa), Nigerian Facilitator 2000-date
(6) Fellow, Natural Science & Engineering
Research Council, Canada
(7) International Society for Study of Xenobiotics,
USA
MEMBERSHIP OF LOCAL BODIES
(1) Consultant, Biokinetic Research Group
(2) Member, West African Society for Pharmacology
(WASP).
EDITORIAL BOARD AND REGISTRATION
(1) Editorial Board Member - Associate Editor
for Africa Region “International Journal of Environmental Research and
Public Health. 1SSN 1660-4601” Molecular Diversity Preservation International,
Basel, Switzerland.
(2) Editorial Advisory Board Member-“Recent
Patents on Anti-infective Drug Discovery” Bentham Science Publishers
Ltd, P.O. Box 640310, San Francisco, CA 94164-0310, USA.
(3) Consulting Editor , American Biographical
Institute, 5126 Burke Oak Circle, Raleigh NC 27612 USA.
(4) External Reviewer: Environment, Lancaster, UK.
(5) External Reviewer: Journal of Raw materials Research, Official organ of Raw materials Research and Development council, Abuja , Nigeria.
(6) External Reviewer: Reproductive Toxicology , Louisville USA
(7)
External Reviewer: Toxicology and Environmental Chemistry, Environmental Chemistry
and Ecotoxicology, University of Bayreuth, Germany
RESEARCH
COLLABORATORS
Professor
Paul-Bernard Tchounwou
Professor and Director of Environmental Science
NHI-Center for Environmental Health
Jackson State University. USA
Email: paul.b.tchounwou@jsums.edu
URL: http://stallion.jsums.edu/~envsci/
Hoffman
Moka Lantum MD,
PhD Toxicologist
Unit Director
Biochemical & Analytical Toxicology
Health and Environmental Laboratories
Eastman Kodak Company, USA.
Hoffman.lantum@kodak.com
Dr
Amadou Diouf Toxicologist
Toxicologue Fac. Medecine, UCAD
Dakar, Senegal.
E-mail: amdiouf@refer.sn
Prof
Jerome Nriagu
School of Public Health
Department of Environmental &Industrial Health
University of Michigan
USA
Email:jnriagu@sph.umich.edu
Travel
Fellowships or Sponsorship to International Conferen/workshop
(1) Name of Conference/Theme:
Environmental Health Conference/Environmental
Health Needs and Research Opportunities for West Africa.
Sponsor: Environmental and Occupational Health Sciences Institute,
EOHSI, USA National Institute of Environmental Health Sciences, NIEHS, USA;
University College, Rutgers, USA.
Role in Conference: Resource person/Symposium speaker
Date/Place: January 3-6, 2001 / University of Legon, Ghana, West Africa
(2)
Name of Conference/Theme:
34th Annual Symposium, Society of Toxicology, Canada
(STC)
Sponsor: Toxicology Research Division, Health
Canada
Role in Conference: Attendee
Date/Place: Dec 6 & 7, 2001/ Holiday Inn,
Montreal, Quebec, Canada
(3)
Name of Conference/Theme:
Radiation Safety Workshop
Sponsor: Canadian Nuclear Commission
Role in Workshop: Trainee
Date/Place: Dec 4 2001, Banting Research Centre,
Ottawa, Canada
(4) Name
of Conference/Theme:
World Conference Antiinfectives/ Paul Ehrlich Symposium
Sponsor: World Conference on Drugs and Antiinfectives
(WCDA) [Part Sponsorship]
Role in Workshop: Attendee
Date/Place: September 6- 12, 2004/ Nurenberg
Germany
(5) Name
of Conference/Theme:
7th International ISSX meeting
Sponsor: International Society for the Study
Xenobiotics [Part Sponsorship]
Role in Workshop: Attendee/ Presentation of
paper.
Date/Place: August 29-September 2 / Vancouver,
Canada
(6) Name of Conference/Theme:
First International Symposium on Recent Advances in Environmental
Sponsor: Center Environmental Health- Environmental
Science PhD programme
Role in Workshop: Symposium speakers.
Date/Place: September 19- 22, 2004/ Jackson
State University, Mississippi.
(7) Name of Conference/Theme: 44th Annual SOT
Meeting
Sponsor: African Society for Toxicological Sciences/African
Education ,Initiative (NEF).
Role in Workshop: Attendee/ Presentation of
paper.
Date/Place: March 6-10, 2005/ Louisiana , New Orleans.
(8)
Name of Conference/Theme:
8th International ISSX meeting
Sponsor: International Society for the Study
Xenobiotics
[Part Sponsorship]
Role in Workshop: Attendee/ Presentation of
paper.
Date/Place: October 23-October 27 / Maui, Hawai,
USA.
RESEARCH AWARD WON
(a)
Canadian Government Laboratory Visiting Fellow 2001-2002.
(b) Nnamdi Azikiwe University, Senate Grant 1995/96.
(c) EVALUATION OF THE MEDICINAL ROLE OF LOCALLY
PRODUCED CARBON BLACK”
Sponsor: RAW MATERIALS RESEARCH AND DEVELOPMENT
COUNCIL, MAITAMA, ABUJA, NIGERIA
Amount: N1,954,150 (12/2003 - 12/2004).
(d)
Heavy metal hazards of Nigerian traditional remedies and investigations of
chronic organ effects.
Sponsor NATIONAL AGENCY FOR FOOD AND DRUG ADMINISTRATION AND CONTROL (NAFDAC)
ABUJA, NIGERIA.
Amount: N4,136,616.00. (07/2004 -2005).
(e) Society of Toxicology- AstraZeneca Award
(2005) on outstanding qualifications as a senior scientist and practice of
toxicology, FROM INTERNATIONAL UNION OF TOXICOLOGY
OTHER
PROFESSIONAL EXPERIENCES
1. Resource person: Toxicology Internship Program,
African Education Initiative, Nduaka Educational Foundation (USA) and National
Institute of Pharmaceutical Research and Development, Abuja, Nigeria.( www.nef3.org)
2. Accredited environmental consultant to Federal Ministry of Environment of the Federal Republic of Nigeria
3.
Accredited environmental consultant to Directorate of Petroleum Resources,
Nigerian National Petroleum Corporation
LIST
OF PUBLICATIONS
(Country in parenthesis indicates where article was published)
1.
Akintonwa. A., Orisakwe O.E. (1988). Adsorption of metronidazole and tinidazole
to activated charcoal and effect of magnesium sulphate. Vet. Hum. Toxicol
30 (6): 556-558. (U. S. A).
2. Akintonwa A., Orisakwe L. O.E. (1990). Effect of activated charcoal
on chloroquine absorption in man. Nig. J. Physiol. Sci. 6 (1): 18-27. (NIGERIA).
3. Akintonwa A., Orisakwe L. O. E (1990). Effect of saline cathartics on the
absorption on sulphamethoxazole to activated charcoal. Arch. Int. Pharmacology
304: 290- 294. (BELGIUM).
4. Orisakwe L.O.E., Akintonwa A. (1991). Comparative adsorption of chloroquine,
mefloquine, isoniazid to activated charcoal and locally produced carbon black.
(220).
West Africa J. Pharmac Drug Res. 4 (Supplement): 35-37. (WEST AFRICA).
5. Orisakwe, L.O.E., Akintonwa A. (1991). Effect of Na2S04 on adsorption of
chloroquine and mefloquine to activated charcoal. East African Med..J. 68
(6). 420-424 (KENYA).
6. Orisakwe L.O.E., Akintonwa (1991). In vitro adsorption studies of isoniazid.
Hum. Exp. Toxicol. 10: 133- 135 (U.K.).
7. Orisakwe L.O.E., Akintonwa A. (1991). Effect of activated charcoal on quinine
absorption in man..Nig. J. Physiol. Sci. (1): 49-53. (NIGERIA).
8 Orisakwe L.O.E., Akintonwa A. (1990).The adsorption of quinine and quinidine
to activated charcoal with and without MgSO4. Vet. Hum. Toxicol. 32 (6): 567-568.
(U.S.A.).
9 Orisakwe L.O.E. (1992). Safety warning and first aid instructions on consumer
and pharmaceutical products in Nigeria. Are they adequate? Hum. Exp. Toxicol.
11(6): 546 548. (U.K).
10 Orisakwe L.O.E. (1994). Activated charcoal. Is Failure to use it negligence
or ignorance?
South Med.. J. 82 (27): 165- 168 (U.S.A.).
11 Orisakwe L.O.E., Obi N. (1993). In vitro and in vivo absorption studies
of diazinon. Hum. Exp. Tox.. 13: 133-135. (U.K).
12. Orisakwe O.E. (1992). Use of activated charcoal to treat poisoning. Trop.
Doc.176-177. (U.K).
13 Orisakwe O.E., E. Ogbonna (1993). Effect of saline cathartics on gastro-intestinal
transit time of activated charcoal. Hum. Exp. Toxicol. 13: 403405. (U.K).
14 Orisakwe O. E. (1992). Negligence of activated charcoal due to lack of
current information. Israel Med.. J. 28 (10): 751-752. (ISRAEL).
15. Orisakwe O.E., Akah P. A., Orish C.N. (1994). Prevalence of parental administration
of drugs to children before coming to the hospital. Trop. Doc. 24:182-183.
(U.K.).
16. Nwobodo E., Okonkwo C., Orisakwe O.E., Obi, E. (1995).
Menarche in Nigeria Ibos. Orient J. Med.. 7(2): 23-25. (NIGERIA).
17 Orisakwe O.E., Dioka E.C., Orish C.N., Okpogba A.N. (1994). Charcoal and
rifampicin pharmacokinetics. Amer. J. Therap. 2: 68- 70. (U.S.A.)
18. Orisakwe O.E., Ofoefule S.I., Dioka,C. E., Ufearo C. S., Nwobodo E.O.
(1995). Carbon Black: A possible role in poison management. Tokai J. Exp.
Clin.. Medicine. 20 (2): 67- 70. (JAPAN).
19. Ufearo C.S., Orisakwe O.E. (1995).Restoration of normal sperm characteristics
in hypoprolactinemic infertile men treated with metoclopamide and exogenous
human prolactin. C1in.. Pharm.. Ther. 58 (3): 354-359. (U.S.A.).
20. Orisakwe O.E., Nwobodo E.O ., Dioka C. E., Okogba A.N. (1995).Effect of
headaches on working ability. An epidemiological survey of automobile industries.
Nig. Med.. J. 29 (2): 56-58. (NIGERIA).
21. Orisakwe O.E., Afonne O.J., Dioka C.E. (1996). Preliminary investigation
of Synclisia scabrida as a folklore medicine in Nigeria. BMSA 7(3):1-5. (JAPAN).
22. Orisakwe O.E. Afonne O.J., Dioka C.E. (1996). A papaverine-like activity
of Synclisia scabrida in Nigerian folklore. BMSA 8(3): 1-5. (JAPAN).
23. Ufearo C. S., Orisakwe O. E., Ogamba J.O., Maduka S.O. (1996). Evidence
for prolactin participation in the control of male fertility. J. Med. Lab.
Sci. 5: 148-152. (NIGERIA.).
24. Orisakwe O. E., Afonne O. J., Dioka C. E., Ufearo C. S., Ofoefule S.I.
(1996). Investigation into the oestrogen-like activity of Synclisia scabrida.
Fitoterapia. LXVII (5): 469- 471. (ITALY).
25. Orisakwe O.E., Dioka C. E., and Ofoefule S.I., (1996). A comparative review
of poisoning in Nigeria. J. W. Afr. Pharm. 10 (2): 53-55. (WEST AFRICA).
26. Orisakwe O.E., Afonne O.J., Dioka C. E., Ufearo C.S., Okpogba A.N., Ofoefule
S.I. (1996). Some pharmacological properties of Synclisia scabrida II. Indian
J. Med. Res. 103: 282-284. (INDIA).
27. Orisakwe O.E., Dioka C.E., Nwobodo E. O., Okonkwo V. C., Anike I.C., Enendu
A. O. (1996). Respiratory abnormalities associated with occupational exposure
to particulate insults in “Okada” (Motorcycle ) operators in Nnewi.
Nig. Med.. Pract. 32(3/4): 36-38. (NIGERIA).
28. Nwobodo E., Orisakwe O. E. Okonkwo C., Dioka C. E., Amilo G. (1997). Dysmenorrhea
amongst school girls and treatment. Orient J. Med. 8 (4): 166-169. (NIGERIA).
29. Orisakwe O. E., Dioka C. E., Okpogba A.N., Orish C.N., Ofoefule S.I. (1996).
Effect of activated charcoal on rifampicin absorption in man. Tokai J. Exp.
Clin. Medicine 21 (1): 51-54. (JAPAN).
30. Orisakwe O.E., Ofoefule S. I. (1996). Plasma and saliva concentration
of rifampicin in man after oral administration. Tokai J. Exp. Clin. Med. 21
(1): 45-49. (JAPAN).
31 Ofoefule S.1., Orisakwe O.E., 1bezim E.C., Esimone C.O. (1998). Mechanism
of nifedipine release from sustained release tablets formulated with some
polymeric materials. Boll. Chim. Farm. 37 (6): 223-227. (ITALY).
32. Orisakwe
O.E., Chilaka K.C., Okpogba A.N. (1997). Plasma levels of aluminum after ingestion
of achara tea (Cympogopon citratus) in human volunteers. Asian Pacific J.
Pharm. 13, 79-82. (SINGAPORE/JAPAN).
33 Ibezim E.C.,Ofoefule S.I., Ejeahalaka C.N.C Orisakwe O.E. (1999). In vitro
adsorption of ciprofloxacin on activated charcoal and talc. Amer. J.Ther.
6: 199-201. (U.S.A).
34 Ofoefule S.I., Nwankwo C, Chukwu A,Orisakwe O.E. (1998). In vitro properties
of ciprofloxacin suppositories formulated with glycerogelatin and theobroma
oil bases. Boll. Chim. Farm. 137 (9): 685-688 (ITALY).
35 Akah P.A., Orisakwe O. E., Gamaniel K.S. (1998). Evaluation of Nigerian
traditional medicine II: effect of some Nigeria folk remedies on peptic ulcer.
J. Ethnopharmac. 62:123- 127 (NETHERLAND /USA).
36 Akah P.A., Orisakwe O.E., Nwafor S.V., Gamaniel K. S. (1998). Prospects
of natural plant product as antiulcer agents. J. Pharm. Res Dev. 3 (2) 57-
62 (NIGERIA).
37. Ofoefule S.I., Orisakwe O.E., Obi E. (1996). A procedural update on .laboratory
diagnostic test and current treatment protocols for immunologically mediated
infertility in the male. Indian. J. Hosp. Pharm. (Accepted for publication)
(INDIA).
38. Orisakwe O.E., Ofoefule S.I., Nwobodo E. (1996). Snuff, harmless substitute
for tobacco? Indian. J. Hosp. Pharm. (Accepted for publication). (INDIA).
39. Ibezim E., Ofoefule S. I., Orisakwe O. E. (1996). A comparative study
of the in vitro adsorption of some drugs on activated charcoal. J. Univ. Sci.
Tech. (Accepted for publication) (GHANA).
40. Orisakwe O.E., Obi E., Amilo G., Dioka C. E., Afonne O.J., Ufearo C. S.
(l997). Sodium and potassium levels and label review studies of Nigeria spices.
Indian J. Nutr. Diet. 37:146-150. (INDIA).
41 Orisakwe O.E., Dioka C. E., Ufearo C. S. (1999). The effect of ovarian
steroid hormones on the prostaglandins metabolism in the rat lung. Afr. J.
Med. Pharm. Sci 1:52-55 (NIGERIA).
42 Orisakwe O. E., Obi E., Asomugha A .L. (1999). Use of neutrophil from cardiac
puncture and wounds smear as ulcer markers. Nig. J. Med. Res. 3:4 (NIGERIA)
.
43 Orisakwe O. E.,Orish C.N., Egenti L. (2000). Childhood non drug poisoning
in
Nnewi, Nigeria. Trop Doc.) 30 209-211 (UK).
44 Ofoefule S.I., Orisakwe O.E., et al (2004). Bioavalability of metronidazole
in rabbits after administration of rectal suppository. Amer. J. Ther 11 (3)
190-193 (U.S.A).
45. Orisakwe O.E., Asomugha R., Afonne O. J., Obi E., Chilaka K.C., Dioka
C. E. (1999). Effect of industrial effluents on soil and water qualities in
Nnewi, Nigeria. J. Health Sci. 45 (4): 177-183 (JAPAN).
46 Orisakwe O.E., Chilaka K.C., Afonne O.J., Obi E., IIondu N. (1999). Evaluation
of the developmental toxicity of amlodipine besylate in mice. J. Health Sci.
46 (1): 42-45 (JAPAN).
47 Afonne O. J., Orisakwe O. E., Ndubuka G.I., Akumka D.D., Ilondu N.D.A.
(2000). Zinc protection of mercury-induced hepatic toxicity in mice. Biol.
& Pharm. Bull. 23(3): 305-308 (JAPAN).
48. Ilondu N., Orisakwe O.E., Ofoefule S.I., Afonne O.J., Obi E., Chilaka
K. C.,Orish C. (2000). Pharmacokinetics of diethylcarbamazine: Prediction
by concentration in saliva. Biol. & Pharm.. Bull. 23 (4): 443-445 (JAPAN).
49. Orisakwe
O.E., Ilondu N.D.A., Afonne O.J., Ofoefule S.I., Orish C.N. (2000). Acceleration
of body clearance of diethylcarbamazine by oral activated charcoal. Pharm.
Res. 42 (2): 167-170. (ITALY).
50. Orisakwe O.E., Akumka D.D., Afonne O. J., Gamaniel K.S. (2000). Investigation
into the pharmacological basis for folkloric use of Bonny light crude oil
in Nigeria. Indian. J. Pharm. 32:231-234 (INDIA).
51. Afonne O.J., Orisakwe O.E., Obi E., Orish C., Akumka D. D. (2000). Some
pharmacological properties of Synclisia scabrida III. Indian J. Pharm. 32:239-241
(INDIA).
52. Obi E. Emeh J.K., Orisakwe O.E., Afonne O.J., Ilondu N.A., Agbasi P.U.
(2000). Invesigation of the biochemical evidence for the antiulcerogenic activity
of Syncliscia scabrida. Indian J. Pharm.32: 381-383 (INDA).
53. Ofoefule S.I., Orisakwe O. E., Onyengba O. (2000). Effect of pefloxacin
on urinary and salivary concentrations of isoniazid (INH) in six healthy female
volunteers.
Amer. J. Ther. 7(5): 313-316 (U.S.A.)
54. Orisakwe O.E., Afonne O.J., Nwobodo E., Asomugha L., Dioka C.E. (2001).
Low- dose mercury induces testicular damage in mice which is protected by
zinc. Eur. J. Obst. Gyn. Rep. Biol. 95(1) : 92-96 (NETHERLAND).
55. Ofoefule S.I., Onuoha C., Okonta M.J., Udeogaranya M., Orisakwe O.E. (2001).
Effect of activated charcoal on isoniazid absorption in rabbits. Bolletino
Chimico Famaceutico 140 (3) 183-186 (ITALY).
56. Orisakwe O.E., Obi E., Emeh J. K. (2000). Antiulceration of Synclisia
scabrida. Neutrophil: An alternative ulcer marker? Asian Pacific Journal 15
(4); 77-81 (JAPAN).
57. Orisakwe O.E., Ilondu N.D.A., Afonne O. J., Ofoefule S.I. Orish C.N. (2001).
Effect of activated charcoal on diethylcarbamazine absorption in human. Am
J Ther 8(1): 7-9
(U. S. A.).
58. Orisakwe O.E., Agbasi P.U., Afonne O.J., Ofoefule S.I., Obi E., Orish
C.N. (2001). Rifampicin pharmacokinetics with and without ciprofloxacin. Am.
J. Ther. 8(3): 151-153 (U. S. A.).
59. Agbasi P.U., Orisakwe O.E., Obi E., Ofoefule S.I., Ilondu N.A., Afonne
O.J. (2001). Effect of sulphate cathartics on adsorption of rifampicin to
activate charcoal. Indian J. Pharmac Sci. (July-August): 328-3330 (INDIA).
60. Ofoefule S.I., Obodo C.E., Orisakwe O.E., Ilondu N.A., Afonne O.J., Maduka
S.O., Anusiem C.A., Agbasi P.U. (2001). Some plasma pharmacokinetic parameters
of isoniazid (INH) in the presence of a fluoroquinolone antibacterial agent.
Am. J. Ther. 8(4): 243-246 (USA).
61. Ofoefule S.I., Obodo C.E., Orisakwe O.E., Afonne O.J., Ilondu N.A., Agbasi
P.U., Anusiem C.A., Maduka S.O., Ilo C.E. (2002). Salivary and urinary excretion
and plasma-saliva concentration ratio of isoniazid (INH) in the presence of
co-administered ciprofloxation (CP). Am. J. Ther. 9 (1): 15-18 (USA).
62.Orisakwe O.E., Agbasi P.U., Ofoefule S.I., Ilondu N.A., Afonne O.J., Anusiem
C.A. Ilo E., Maduka S.O. (2004). Effect of pefloxacin on the urinary excretion
of rifampicin. American Journal of Therapeutics 11(1) 13-16 (USA).
63. Orisakwe O.E., Asomugha R., Obi E., Afonne O.J., Dioka C.E., Akumka D.D.,
Ilondu N.A. (2001). Ecotoxicological study of the Niger-Delta area of the
River Niger. Bull. Environ. Contam. Toxicol. 66(4): 548-552 (USA).
64. Orisakwe O.E., Afonne O.J., Agbasi P.U., Ilondu N.A. Ofoefule S.I. Obi
E (2001). Adsorptive capacity of activated charcoal for rifampicin with and
without sodium chloride and sodium citrate. Biol. Pharm. Bull. 24 (6): 724-726
(JAPAN).
65. Chude M.A., Orisakwe O.E., Afonne O.J., Gamaniel K.S., Vongtau O.H., Obi
E. (2001). Hypoglycemic effect of the aqueous extract of Boerhavia diffusa
leaves. Indian J. Pharm. 33: 215-216 (INDIA).
66. Afonne O.J., Orisakwe O.E., Obi E., Dioka C. E., Ndubuka G. I. (2001).
Nephrotoxic actions of low-dose mercury in mice: protection by zinc. Arch.
Environ. Health 57(2): 98-102 (U.S.A.).
67. Orisakwe O. E., Oluboyo A., Ofoefule S., Obi E., Ilondu N., Afonne O.J.,
Agbasi P., Chiroma D.H. (2001). Adsorption studies of artesunate: Evaluation
of saline cathartics as additive in management of artesunate poisoning. J.
Health Sci. 47(5): 1-4 (JAPAN).
68. Afonne O. J., Orisakwe O.E., Ekanem I A., Akumka D.D. (2002). Zinc protects
chromium-induced testicular damage in mice. Indian J. Pharm. 34: 26-31 (INDIA).
69. Orisakwe O.E., Afonne O.J., Ilondu N., Obi E., Ufearo C. S., Agbasi P.
U., Maduka S. O., Orish C. N., Orish V.N. (2002). Influence of prokinetics
on the gastrointestinal transit and residence times of activated charcoal.
Journal of the Pakistan Medical Association. 52 (8) 354-358 (PAKISTAN).
70. Orisakwe O.E., Afonne O.J., Dioka C.E., Agbasi P.U., Obi E. (2002). Testicular
toxicity of rinbacin in rats. Biol. Pharm. Bull. 25(2): 206-208 (JAPAN).
71. Afonne O.J., Orisakwe O.E., Ofoefule S.I., Tsalha S., Obi E., Ilondu N.A.,
Okorie O. (2002). Saline cathartics and adsorptive capacity of activated charcoal
for doxycyline. Acta Poloniae Pharmaceutica Drug Research 59(3): 177-179 (POLAND).
72. Afonne O.J., Orisakwe O.E., Dioka C.E., Obi E., Ezejiofor T., Asomugha
L., Ukoha U., (2002). Effects of rinbacin on rat kidney. Biol & Pharm
Bull 25(8): 1022-1025 (JAPAN).
73. Dioka C.E., Orisakwe O.E., Afonne O.J., Agbasi P.U., Akumka DD., Okonkwo
C.J., Ilondu N. (2002). Investigation into the haematologic and hepatic effects
of rinbacin in rats. J Health Sci 48(5): 393-398 (JAPAN).
74. Afonne O.J. and Orisakwe O.E (1999) Cytokines in Environmental toxicology.
Trop J Med. Res. (3) 1-8 (NIGERIA).
75. Orisakwe
O.E., Afonne O.J., Chude M.A., Obi E., Ilondu N.A., Dioka C.E. (2003). Subchronic
toxicity studies of the aqueous extract of Boerhavia diffusa leaves. J Health
Sci 49(6) 444-447 (JAPAN)
76. Orisakwe O.E., Agbasi P.U., Afonne O.J., Orish C.N., Ilondu N.A., Obi
E. (2004). Urinary excretion of rifampicin in the presence of ciprofloxacin.
American J Ther. 11(3) 171-174 (USA)
77. Orisakwe O.E., Asomugha R., Obi E., Afonne O.J.,Anisi., Dioka C.E. (2004).
Impact of effluents from car battery manufacturing plant on water, soil and
food qualities in Nnewi, Nigeria. Arch. Environ. Health (Accepted for Publication)
(USA).
78. Orisakwe O.E., Hussaini D.C., and Afonne O.J (2004) Testicular effects
of sub-chronic adminustration of Hibiscus sabdariffa calyx aqueous extract
in rats. Repro Tox. 18 (2) 295-298 (USA).
79. Dioka
CE, Orisakwe OE ,Adeniyi FAA, and Meludu SC. (2004) Liver and renal function
tests in occupationally lead exposed artisans in mechanic village in Nnewi,
Nigeria. Int J Env Res & Pub Health 1 19-23 (USA).
80. Orisakwe O. E, Njan A A, Afonne O. J, AkumkA D. D, Orish V. N, Udemezue
O. O (2004) Investigation into the Nephrotoxicity of Nigerian Bonny light
Crude oil in Albino rats. Int J Env Res & Pub Health 2 ,91-95 (USA).
81. Orisakwe O.E., Afonne O.J., Ezejiofor N.A., Tsalha S. (2003). In vitro effects of sulphate cathartics on the adsorption of doxycycline to activated charcoal Eur Bull Drug Res 11 (4) 93-98 (Italy).
82. Orisakwe O.E., Hussaini D.C.,Orish V.N; Obi E; Udemezue .O., (2003) Nephrotoxic effects of Hibiscus sabdariffa calyx in rats Eur Bull Drug Res 11 (4) 99-104 (Italy).
83. Orisakwe O.E. E. Obi , V.N Orish, O.O. Udemezue (2003) Effect of halofantrine on testicular architecture and testosterone level in guinea pigs Eur Bull Drug Res 11 (4) 105-109 (Italy).
84. Orish.E .Orisakwe , Dora N. Akunyili ., Patrick.U Agbasi Ndidi.A. Ezejiofor (2003). Some plasma and saliva pharmacokinetics parameters of rifampicin in the presence of Pefloxacin American J Ther. 11 (4):283-287 (USA)
85. Orisakwe
O.E., Akumka D.D., Njan A.A and Afonne O.J (2004). Testicular toxicity of
Nigerian bonny-light crude oil in male albino rats. Repro Tox. 18 (3): 439-442
(USA)
86. Hussaini D. C, Orisakwe
O. E , Njan A.A., Akumka D. D , Udemezue O. O, (2004) Subchronic administration
of Nigerian specie of aqueous extract of hibiscus sabdariffa calyx in rats
did not produce cardiotoxicity Eur Bull Drug Res 12 1-5 (Italy).
87. E. Obi, Orisakwe O.E., L. A Asomugha, V.N Orish, O.O. Udemezue and N.A. Ezejiofor (2004) Hepatotoxicity of halofantrine in guinea pigs Ind J Pharmac (Accepted for Publication) (INDIA)
88. Ifeyinwa
C. Olife , Antoinette N.Okaka, Chudi E. Dioka, Samuel C. Meludu, Obi Ejeatuluchukwualo,
Orish E. Orisakwe (2005). Iodine Status and effect of soil erosion on trace
elements in Nanka and Oba towns of Anambra State, Nigeri Int J Env Res &
Pub Health (Accepted for publication) (USA).
89. Rose Asomugha, Orish E. Orisakwe, Onyenmechi J. Afonne, Ejeatuluchukwu
Obi, John C. Nduka, Chudi E. Dioka (2005). Impact of effluents from cable
manufacturing plant on food, water and soil qualities in Nnewi, Nigeria. Pakistan
J Biol Sci (Accepted for publication) (PAKISTAN).
90. O.E Orisakwe, D. D. Akumka, A. A. Njan, O. J. Afonne, O.O. Okechi (2005)
Hepatotoxic and haematological effects of Nigerian bonny light crude oil in
malealbino rat Toxicology and Environmental Chemistry (GERMANY)
91. Ilo.E.C, Orisakwe O.E , Ilondu N.A, Okwoli N , Brown S.A, Elo-Ilo J.C.(2005). Effect of Chloroquine on the bioavalability of ciprofloxacin in man. American J Ther (Accepted for publication) (USA).
PAPERS UNDER REVIEW
1. O.E.Orisakwe,
E. Obi, D. N. Akunyili, B.O. Ekpo and H.M. Lantum (2004) Heavy metals hazards
of Nigerian Herbal Remedies, Toxicologist (USA)
2. O.E.Orisakwe, E. Obi, J. Harry and Debem H (2005) Toxicologic pathology
of halofantrine on guinea pig kidney Biomed Central Pharmac (USA)
3. Orisakwe O.E., Dioka C.E., and Adeniyi F.A.A. (2005) Zinc protection of
testicular
toxicity of lead in guinea pig. Asian Journal of Andrology (CHINA)
4. O.E.Orisakwe,
E. Obi , D. N. Akunyili (2005) Safety warnings and first aid instructions
on Nigeria traditional herbal remedies: are they adequate? Clin Pharm Ther
(USA)
5. Ilo ELO C, Orisakwe O.E , Ilondu N.A, Okwoli N , Brown S.A.( 2005) Urinary
excretion pattern of Chloroquine and Ciprofloxacin when taken alone and in
combination. Amer. J. Therap (USA).
6. ZETA-121 and Orisakwe O. E (2005) Labeling and certification on commonly consume beverages in Nigeria: are they adequate? . Amer. J. Therap (USA).
SOME RECENT CONFERENCE ABSTRACTS
1. Orisakwe
O.E. et al (1995). Procedural update on laboratory diagnostic test and current
treatment protocols for immunologically mediated infertility in the male.
21st Annual Scientific Conference of the Nigeria Society for Immunology. November
19 -22, 1995.
2. Orisakwe O.E. et al (1995). Therapeutic Challenges on HIV infections: A
raging battle: Presented at the 21st Annual Scientific Conference of the Nigeria
Society for Immunology November 19 -22, 1995.
3. Orisakwe O.E., Afonne O.J. (1997). Investigation into the effects of selenium
and hexavalent chromium on murine testis. 24th Annual Regional Conference
of the West African Society for Pharmacology (WASP).
4. Orisakwe O.E., Afonne O.J., Chilaka K.C., Obi E. (1998). Evaluation of
the testicular toxicity of hexavalent chromium and effects of zinc 11 in mice.
C0022. 19th Annual Meeting of SETAC. Charlotte NC.
5. Akumka D.D., Orisakwe O.E., Amos S., Ose J.T., Afonne O.J., Obi E., Gamaniel
K.S. (1999). Does bonny light crude oil cause testicular toxicity? 26th Annual
Regional Conference of the West African Society for Phamacolocology (WASP).
Nsukka, Nigeria. October 20-23,1999.
6. Akumka D.D., Orisakwe O.E., Amos S., Ebute C.P., Afonne O.J., Adamu M.,
Njan A.A., Gamaniel K.S. (1999). Effect of bonny light crude oil on rat liver
and liver enzymes. 26th Annual Regional Conference of the West African Society
for Pharmacology (WASP). Nsukka, Nigeria. October 20-23,1999.
7. Pam H.C., Husaini D.C., Ajoku G., Orisakwe O.E., Gamaniel K.S. (2000).
Some toxic effects of Hibiscus sabdariffa. 27th Annual Regional Conference
of the West African Society for Phamacology (WASP). Port-Harcourt, Nigeria.
October 23-28-2000.
8. Obi E., Orisakwe O.E., Odike M., Asomugha R., Asomugha L., Afonne O.J.,
Ilondu N.A., Agbasi P.U., Ukoha U. (2000). Toxicologic pathology of halofantine
on guinea pig. 27th Annual Regional Conference of the West African Society
for Pharmacology (WASP). Port-Harcourt, Nigeria. October 23-28, 2000.
9. Asomugha R., Asomugha L.A., Ukoha U., Maduka S.O., Orish V.N., Obi E.,
Afonne O.J., Orisakwe O.E. (2000). Splenic and haematologic effects of artesunate
in guinea pig. 27th Annual Regional Conference of the West African Society
for Pharmacology (WASP). Port-Harcourt, Nigeria. October 23-28, 2000.
10. Orisakwe O.E., Ilo E.C., Afonne O.J., Ofoefule S.I., Ilondu N.A., Agbasi
P.U., Obi E., Maduka S.O. (2000). Effect of Chloroquine on the urinary excretion
of ciprofloxacin. 27th Annual Regional Conference of the West African Society
for Pharmacology (WASP). Port-Harcourt, Nigeria. October 23-28, 2000.
11. Husaini D.C., Pam H., Ukoha U., Afonne O.J., Orisakwe O.E., Gamaniel K.S.
(2000). Hepatotoxicity study of Hisbiscus sabdariffa in rats. 27th Annual
Regional Conference of the West African Society for Pharmacology (WASP). Port-Harcourt,
Nigeria. October 23-28,2000.
12. Orisakwe O.E., Asomugha R., Afonne O.J., Obi E., Husaini D.C. (2001).
Impact of effluents from lead battery and cable manufacturing plants on soil,
water and food qualities. Environmental Health Conference, Ghana. January
3-6 2001.
13. Asomugha R., Orisakwe O.E., Afonne O.J., Obi E. (2001). Environmental
effects of effluents from petroleum processing industry. Environmental Health
Conference, Ghana. January 3-6, 2001.
14. Husaini D.C., Asomugha R., Orisakwe O.E. (2001). Impact of effluents from
palm and kernel oil processing factory on water, soil and food qualities.
Environmental Health Conference, Ghana. January 3-6, 2001.
15. Afonne O.J., Pam H.C., Orisakwe O.E. (2002). Health effects of exposure
to some heavy metals in mechanic workshops. 29th Annual Regional Conference
of the West African Society for Pharmacology (WASP). Abuja, Nigeria. October
21-23, 2002.
16. Orish
E. Orisakwe and Ejeatulu Obi Heavy metal hazard of Nigerian traditional remedies
7th International International Society for the Study Xenobiotics meeting
Vancouver, Canada August 29- September 2, 2004
TECHNICAL REPORT SUBMITTED TO GOVERNMENT AGENCY IN NIGERIA.
ORISH EBERE ORISAKWE (2005). Report of study on evaluation of the medicinal role of locally produced carbon black
COURSES TAUGHT IN POSTGRADUATE (MSc)
1 . Pharmacokinetics
PHA 700 3 Credits
2 . Neurotransmission and ANS PHA 701 4 Credits
3 . Immunopharmacology PHA 702 3 Credits
4 . CNS Pharmacology PHA 703 3 Credits
5 . Principles of Chemotherapy PHA 704 3 Credits
6 . Toxicology PHA 705 3 Credits
7 . Cardiovascular Pharmacology PHA 706 4 Credits
8 . Endocrine Pharmacology PHA 707 4 Credits
9 . Renal Pharmacology PHA 708 3 Credits
10. Seminar PHA 709 3 Credits
11. Research Project PHA 710 12 Credits
PhD COURSES TAUGHT.
1. Advances in Neuropharmacology PHA 803
2. Advances in Toxicology PHA 805
3. Advances in Chemotherapy PHA 806
MEMBERSHIP OF SENATE AND VICE CHANCELLOR’S COMMITTEES
1.
Inaugural Lectures committee (Member); 2003-
2. International Linkage committee (Member);
2003-
CONTRIBUTION TO THE UNIVERSITY SYSTEM.
•
Introduction and Nurturing
of Toxicology Unit.
• Introduction
and Nurturing of Animal House
• Introduction
and Nurturing of Postgraduate Programme
• Organization
of Toxicology Workshop On the Handling and Management of Toxic
Substance.
• Organization
of Toxicology Workshop on the Prevention and control of AIDS.
• Participated
in the three (3)-tier accreditation in the College of Health Sciences,
Nnamdi Azikiwe University, Nnewi Campus.
• Participated
in the three (3)-tier accreditation in the College of Health Sciences, Abia
State University, Uturu, Abia State.
• Foundation
Staff Pharmacology Dept., College of Health Sciences, Nnamdi Azikiwe University,
Nnewi Campus.
• Associate
Lecturer, Pharmacology Dept., Abia State University Medical
School, 1993-1997.
• University
Senator 1992-2000.
• Faculty Examination
Officer. 1992-1995.
• External Examiner,
Dept. of Pharmacology, Abia State University Medical School, 1998
• Approved postgraduate
degree supervisor.
• Resource Person,
University Committee on Staff Harmonization
• Nominated
four postgraduate students of Department of Pharmacology, Nnamdi Azikiwe University
to the membership of ASTS who won four out of the five scholarship positions
sponsored by the Third World Medical Foundation.
• External Examiner,
Department of Pharmacology, Ebonyi State University, 2000-.
• External
Examiner , Department of Pharmacology, University of Port HARCOURT, 2004-.
SERVICE TO THE COMMUNITY
•
Public Lecture/Workshop on
Awareness of AIDS Prevention and Control.
• Creation of
Awareness on Living in a Chemical World.
• Creation of
Awareness on the Toxicology of Particulate Insults amongst Commercial Motorcyclists
REFEREES
Adebayo Oyekan DVM, PhD
Director, Center for Cardiovascular Diseases Research
College of Pharmacy and Health Sciences
Texas Southern University
3100 Cleburne Avenue
Houston TX 77004
Tel: 713 313 4258
Fax: 713 313 4342
E-mail: Oyekan_AO@TSU.edu
Dr Gerard M. Cooke
Health Canada,
Toxicology Research Division
Banting Research Centre
PL 2202D1 Tunney’s pasture
OTTAWA ON
K1A 0L2
E-mail: Gerard_ Cooke@hc-sc.gc.ca
Fax: (613) 941-6959
Hoffman Moka Lantum MD, PhD Toxicologist
Unit Director
Biochemical & Analytical Toxicology
Health and Environmental Laboratories
Eastman Kodak Company, USA.
E mail: hoffman.lantum@kodak.com
Chudy I. Nduaka DVM, PhD, DABT
President, African Education Initiative.
Email: chudy@nef3.org
www.nef3.org
Prof Jerome Nriagu
School of Public Health
Department of Environmental &Industrial Health
University of Michigan
USA
Email: jnriagu@sph.umich.edu
RECORDS OF SUPERVISION
NAME: OBI E.
TOPIC: Investigation into the Biochemical Basis
of the Antiulcer Property of Synclisia scabrida (Miers)
DEGREE /DATE: MSc BIOCHEMISTERY 1997
NAME:
AFONNE O. J.
TOPIC: Dose Zinc Protect Against Mercury-induced
Testicular, Hepatic, Renal and
Splenic Damage in Mice?
DEGREE/DATE: MSc PHARMACOLOGY & TOXICOLOGY,
1998
NAME:
CHILAKA K.C.
TOPIC: Evaluation of Sub-Chronic and Developmental
Toxicities of Amlodipine besylate in Mice.
DEGREE/DATE: MSc PHARMACOLOGY & TOXICOLOGY,
1998
NAME:
AKUMKA D. D.
TOPIC: Evaluation of the Testicular Toxicity
of Bonny Light Crude Oil in Rats
DEGREE/DATE: MSc PHARMACOLOGY & TOXICOLOGY
/1999
NAME:
NJAN A. A.
TOPIC: Nephrotoxicity and Hepatotoxicity of Bonny
Light Crude Oil in Rats
DEGREE/DATE: MSc PHARMACOLOGY & TOXICOLOGY/1999
NAME:
ILONDU N. D. A.
TOPIC: Pharmacokinetics of Diethylcarbamazine:
Prediction from Saliva Sample
DEGREE/DATE: MSc PHARMACOLOGY & TOXICOLOGY/1999
NAME:
ANUSIEM C.
TOPIC: Pharamacokinetics of New Fluoroquinolones
DEGREE/DATE: MSc PHARMACOLOGY & TOXICOLOGY/1999
NAME:
AGABSI P.U.
TOPIC: Influence of Ciprofloxacin and Pefloxacin
on Rifampicin Pharmacokinetics.
DEGREE/DATE: MSc. PHARMACOLOGY & TOXICOLOGY/1999
NAME:
CHUDE M.A.
TOPIC: Toxicological and Hypoglycaemic Effects
of the Leaf Extract of Boerhevia diffusa in Rats
DEGREE/DATE: MSc PHARMACOLOGY & TOXICOLOGY/2000.
NAME:
ILO ELO
TOPIC: Pharmacokinetic Drug Interactions of Chloroquine
and Ciprofloxacin.
DEGREE/DATE: MSc. PHARMACOLOGY & TOXICOLOGY/2000
NAME:
DIOKA CHUDI EMMA
TOPIC: Lead toxicity in occupationally exposed
human subjects and the protective role of zinc in guinea pigs.
DEGREE/DATE: PhD Chemical Pathology, UNIVERSITY
OF IBADAN, IBADAN
NIGERIA / 2003 (cosupervision).
NAME:
OLIFE IFEYINWA CHIDIOGO.
TOPIC: Prevalence of iodine and some trace elements
in some selected populations in Oba and Nanka, Anambra state Nigeria.
DEGREE/DATE:
MSc Biochemistry, Nnamdi Azikiwe University, Awka/ 2004 (cosupervision).
ON-GOING SUPERVISIONS
NAME:
Obi E
TOPIC: Investigation in to the male reproductive
effects of Nigerian herbal remedies
DEGREE/DATE: PhD PHARMACOLOGY & TOXICOLOGY/2002-2005.
NAME:
AFONNE O. J.
TOPIC:Investigations into the testicular mechanisms
of Nigerian crude oil samples in male guinea pigs.
DEGREE/DATE: PhD PHARMACOLOGY & TOXICOLOGY,
2002-2005